Alliance for Pandemic Preparedness

Result for
Topic: Public Health Policy and Practice


February 18, 2020

Do not violate the International Health Regulations during the COVID-19 outbreak

Habibi et al. reflect on potential violations of the International Health Regulations, in particular Article 43 which restricts what measures countries can implement when responding to public health risks, requiring that the measures by “supported by science, in commensurate with the risks involved, and anchored in human rights.” Habibi et al. (Feb 13, 2020). Do…


Authoritarianism, outbreaks, and information politics

In this brief commentary, Kavanagh discusses the potential effects of autocratic and information politics on successful and rapid outbreak response.  Kavanagh (Feb 13, 2020). Authoritarianism, outbreaks, and information politics. The Lancet. https://doi.org/10.1016/S2468-2667(20)30030-X


Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China

An evacuation of 126 persons from Wuhan to Frankfurt, Germany, employed a symptom-based screening process that failed to detect 2 persons who subsequently tested positive for COVID-19. Neither patient developed fever nor respiratory symptoms during 7 days of hospitalization suggesting the potential for viral shedding among asymptomatic or mildly symptomatic people. Hiehl et al. (Feb…


February 14, 2020

Three Emerging Coronaviruses in Two Decades: The Story of SARS, MERS, and Now COVID-19

SARS, MERS, and COVID-19 outbreaks and related clinical and public health response activities are compared and contrasted in this brief commentary.  Guarner (Feb 13, 2020). Three Emerging Coronaviruses in Two Decades: The Story of SARS, MERS, and Now COVID-19. Am J Clin Pathol. https://doi.org/10.1093/ajcp/aqaa029 


Straining the System: Novel Coronavirus (COVID-19) and Preparedness for Concomitant Disasters

This commentary outlines strengths of the U.S. public health system in responding to the COVID-19 outbreak.  Smith and Fraser (Feb 13, 2020). Straining the System: Novel Coronavirus (COVID-19) and Preparedness for Concomitant Disasters. AJPH. https://doi.org/10.2105/AJPH.2020.305618


Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak

Researchers discuss isolation, quarantine, and social distancing as successful tools used during the SARS outbreak and raise key questions that must be answered to determine if these measures would be effective in halting the current COVID-19 outbreak. Wilder-smith and Freedman (Feb 13, 2020). Isolation, quarantine, social distancing and community containment: pivotal role for old-style public…


February 13, 2020

Potentially highly potent drugs for 2019-nCoV

Researchers reviewed 1,465 FDA-approved drugs for potential efficacy in treating COVID-19, quantifying binding affinity and using machine learning methods. The highest scoring options were Bortezomib, Flurazepam, and Ponatinib. Nguyen et al. (Feb 5, 2020). Potentially highly potent drugs for 2019-nCoV. Pre-print downloaded Feb 13 from https://www.biorxiv.org/content/10.1101/2020.02.05.936013v1


Interventions targeting air travellers early in the pandemic may delay local outbreaks of SARS-CoV-2

Clifford et al. examine the effectiveness of air travel-related intervention at preventing 2019-nCoV outbreaks in previously unaffected regions. They examine screening for symptoms at departure or arrival, sensitization of arrivals to signs of illness, and a combination of both practices. This information is combined with R0 estimates and number of infected travelers arriving on a…


US Emergency Legal Responses to Novel Coronavirus Balancing Public Health and Civil Liberties

In this JAMA commentary, Gostin and Hodge discuss the balance of public health protections and civil liberties in the U.S. and the legitimacy of quarantine powers outlined in the Public Health Services Act.  Gostin and Hodge (Feb 13, 2020). US Emergency Legal Responses to Novel Coronavirus Balancing Public Health and Civil Liberties. JAMA Viewpoint. doi:10.1001/jama.2020.2025…


February 12, 2020

Healthcare-resource-adjusted vulnerabilities towards the 2019-nCoV epidemic across China

Given that limited healthcare resources have become a serious bottleneck to the Wuhan epidemic response, an SEIR modeling approach was combined with a healthcare-resource-adjusted vulnerability index to inform public health planning for constrained healthcare resources in this epidemic response. In addition to identifying vulnerabilities across 100 cities in China, the framework provided integrates human movements…



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