Alliance for Pandemic Preparedness

Result for
Topic: Transmission


November 9, 2020

Intergenerational Residence Patterns and Covid-19 Fatalities in the EU and the US

A study using aggregate data from 29 European countries and all 50 US states reported a positive correlation between intergenerational co-residence (age 18−34 years living with their parents) and COVID-19 mortality. On average, each additional percent increase in intergenerational co-residence was associated with a 3-4% increase in cumulative deaths from COVID-19 40-100 days following the…


November 6, 2020

A SARS-CoV-2 Outbreak Illustrating the Challenges in Limiting the Spread of the Virus — Hopi Tribe, May–June 2020

After 2 members of the Hopi tribe tested positive for SARS-CoV-2, among 58 of their primary and secondary contacts (immediate and extended family and community members), 27 (47%) laboratory-confirmed SARS-CoV-2 infections occurred. Among all 29 infected individuals, 22 (76%) were symptomatic and seven were asymptomatic. The majority of people who had presymptomatic and asymptomatic infection…


Network Characteristics and Visualization of COVID-19 Outbreak in a Large Detention Facility in the United States — Cook County, Illinois, 2020

A network analysis of the movements of detained persons and staff members during an outbreak of SARS-CoV-2 in a Chicago jail found that the systematic identification and isolation of infected persons was likely effective at limiting transmission. The movement patterns and connections of 5,884 persons (65% detained persons and 35% staff members) at the jail…


November 5, 2020

Repeated Cross-Sectional Sero-Monitoring of SARS-CoV-2 in New York City

Repeat cross-sectional serosurveys conducted from February to July of residual clinical samples from two patient groups in a New York Hospital — 1) an urgent care (UC) group, enriched with COVID-19 cases, and 2) a routine care (RC) group, which resembles the general population — identified seropositive samples from mid-February, though the first case of…


COVID-19 Risk Management and Screening in the Penitentiary Facilities of the Salerno Province in Southern Italy

In serological and molecular testing of inmates and personnel in an Italian prison with rapid serological IgG/IgM tests for SARS-CoV-2, 3 of 485 prisoners had positive serology results. New prisoners had been isolated for 14 days. All prisoners and personnel had negative nasopharyngeal swabs. Pagano et al. (Oct 31, 2020). COVID-19 Risk Management and Screening…


Favorable Outcomes among Neonates Not Separated from Their Symptomatic SARS-CoV-2-Infected Mothers

In France, among 26 SARS-CoV-2 positive mothers and their neonates, nasopharyngeal and anal swabs from neonates at birth, day 3, and weekly if hospital stay was prolonged, only detected one positive PCR test in an anal swab at birth; nasopharyngeal swabs were negative at day 0 and 3. The infant never developed symptoms. None of…


SARS-CoV-2 Transmission during Team-Sport Do Players Develop COVID-19 after Participating in Rugby League Matches with SARS-CoV-2 Positive Players

[Pre-print, not peer-reviewed] Player interaction and proximity analysis of 4 professional rugby matches in which 8 players were retrospectively found to have SARS-CoV-2 suggest that risk of in-game transmission may be minimal. While video footage analysis and GPS data show the positive players were within 2 meters of other players for up to 316 seconds…


Household Transmission of SARS-COV-2 Insights from a Population-Based Serological Survey

[Pre-print, not peer-reviewed] A household serological survey conducted in Geneva from April to June (n=2,267 households) estimated a 17.2% risk of being infected with SARS-CoV-2 by a single household member compared to a 5.1% cumulative infection risk (through June 30th) from exposures outside the household. Infection risk from an infected household member increased with age,…


Clinical Characteristics of Recovered COVID-19 Patients with Re-Detectable Positive RNA Test

Among 262 patients with COVID-19, 14.5% were found to be re-detectable positive (RP) after at least 14 days of follow up. Most RP patients were young (under 60), initially had mild to moderate illness, and had earlier RNA-negative conversion from illness onset (less than 3 weeks) than non-RP patients. All RP patients were readmitted for…


November 3, 2020

Association between Living with Children and Outcomes from COVID-19 an OpenSAFELY Cohort Study of 12 Million Adults in England

[Pre-print, not peer-reviewed] A population-based cohort study in England found that living with children was not associated with adverse COVID-19 related outcomes. Additionally, no consistent changes in risk were observed following school closure. Among 9 million adults ≤65 years old, living with children age 0-11 years was not associated with increased risk of recorded SARS-CoV-2…



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