William M. Atkins

Chair;

The Sidney D. Nelson Professor, Medicinal Chemistry

 

 

 


Contact Info:
Bill Atkins
PH: 206 685 0379

winky@u.washington.edu

WELCOME TO THE ATKINS LAB



FRONT ROW: Amanda Clouser, Michelle Redhair, Hayli Larsen, Lorela Paço.
BACK ROW:
Bill Atkins, Dennis Goulet, Mike Dabrowski.


NEWS FROM FORMER ATKINS LAB MEMBERS

This is never a complete update, but here is some news from former lab members who have recently checked in. Please write in with news any time!

Mavis Li, Ph.D. (2017) is a Postdactoral Fellow at Janssen Pharmaceutical Companies of Johnson & Johnson in the San Diego area.

Hyewon Kwon (2016) is a Research Scientist in the greater San Diego area.

Wynton McClary, Ph.D. (2016) is a Postdoc at the University of Colorado, Denver, in the School of Pharmacy.

Nick Treuheit, Ph.D. (2015) is a Research Scientist in Biosimilar Characterization at Pfenex Inc. ib the San Diego area.

Kip Conner, Ph.D. (2013) is a Scientist at Amgen, San Francisco area.

Matt Honaker, Ph.D. (2012) is currently a Data Scientist at BSQUARE.

Tasha Ritchie, Ph.D. (2011) is now a Research Scientist with the Drug Interaction Database at the UW.

Laura Shireman, Ph.D. (2010) is currently a Research Coordinator and Scientist in the Pharmacokinetics Lab here at the University of Washington.

Joe Zolnerciks, Ph.D. (2009) is now VP of Business Developmentat Solvo Biotechnology.

Larissa Balogh, Ph.D. (2009) is currently a medical writer at Vertex Pharmaceuticals where she works on clinical regulatory documents. Larissa is enjoying her new role, learning a lot and says her MedChem background has proved particularly helpful for ADME and DDI studies.

Abhi Nath, Ph.D. (2008) has taken a position as an Assistant Professor here at UW Med Chem, after postdoctoral training with Liz Rhoades and Andrew Miranker at Yale University. He is very excited to be back in Seattle, and to continue his research on the broad importance of protein dynamics to function and dysfunction.

Art Roberts, Ph.D. (2008) is an Assistant Professor at the University of Georgia Department of Pharmaceutical and Biomedical Sciences.

Liming Hou, Ph.D. (2007) is now a Principal Regulatory Documentation Scientist at Genetech.

Jed Lampe, Ph.D. (2007) says 'Hello from Kansas!' 2013 has been a busy year in the Lampe Lab at the University of Kansas Medical Center. Jed now has two graduate students and they have just submitted the lab’s first original research manuscript entitled, “Common drugs inhibit human OCT1-mediated neurotransmitter uptake”. Jed has also gone back to cytochrome P450 science and is examining the brain-specific cholesterol hydroxylase CYP46A1 and its relationship to traumatic brain injury. When Jed’s not working in the lab, he can be found playing in the park with his 3 year old daughter Raphaella (who loves bugs) or spending time with his beautiful French wife Sylvie and getting fat on her delicious home-cooked meals!

Sumit Mahajan, Ph.D. (2006) is now Director, Drug Development and Diagnostics at Globavir Biosciences, San Francisco.

Josh Pearson, Ph.D. (2006) is Director Preclinical at Amgen, San Francisco area, in the Department of Pharmacokinetcs and Drug Metabolism. Within the Biochemistry and Biophysics subgroup, Josh focuses on elucidating the effects biology and disease have on drug dispositon and clinical efficacy.

Catherine Ibarra Drendall, Ph.D. (2002) is a Senior Scientist at Covance, Immunochemistry.

Bob Lyon, Ph.D. (2002) is Senior Director of Chemistry at Seattle Genetics.

Brenda Nieslanik Kelly, Ph.D. (2000) is Professor, Provost and Dean of the College at Gustavus Adolphus College in St. Peter, MN.

Lisa Storch Goldberg, Ph.D. (1998) resides in Seattle with her husband and two daughters. She divides her time between raising her children, developing an introduction to science program for preschoolers, and tutoring chemistry.

RESEARCH INTERESTS

TECHNIQUES AND INSTRUMENTS

We use a wide variety of spectroscopic and analytical techniques in the course of our research. We own a Fluorolog Tau-3 frequency-domain instrument for time-resolved fluorimetry and an Applied Photophysics SX.18MV-R for stopped-flow fluorescence and absorbance measurements.

We share a number of instruments with the rest of the Medicinal Chemistry Department, including a Varian 500 MHz Unity Inova NMR, absorbance spectrophotometers (an Olis Modernized Aminco DW-2 and a Cary 3E), and facilities for protein expression in bacterial and insect-cell systems.

We have access to several mass spectrometry instruments via the Department's Mass Spectrometry Center, as well as several additional NMR instruments (a 750 MHz, a 500 MHz, and two 300 MHz) via the Dept. of Chemistry NMR facility. We provide access to and training on AUC, DSC, ITC and SPR instrumentation for biophysical characterization studies. These instruments are part of the Molecular Analysis Facility located in the Molecular Engineering and Sciences Institute . We also have access to nanoscale characterization and fabrication tools (atomic force microscopy, electron microscopy and confocal fluorescence microscopy) at the Nanotech User Facility and the Dept. of Pathology Electron Microscopy Center.

USEFUL LINKS

DATABASE & LIBRARY SEARCHES (UW restricted)

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