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WELCOME TO THE ATKINS LAB
FRONT ROW (left to right): Caleb Woods, Hyewon Kwon,
Bill Atkins, Mike Dabrowski, Kip Conner, Tasha Ritchie.
BACK ROW: Joe Tsun, Mauro Acchione, Michele Scian, Matt Honaker.
News from former Atkins Lab members
This is never a complete update, but here is some news from former lab members who
have recently checked in. Please write in with news any time!
Laura Shireman (Ph.D. 2010) recently defended her thesis concerning the
interactions of hydroxynonenal with Glutathione S-transferases. She is
currently doing postdoctoral work in the Department of Pharmaceutics here
at the University of Washington.
Liming Hou, Ph.D. has been working at Abbot Vascular, Inc. as a
Clinical Scientist/Medical Writer since October 2010. Her primary
responsibility is writing and editing peer-reviewed journal
publications and supporting conference presentations. She is
learning a lot about medical device development and marketing,
and heart disease.
Larissa Balogh, Ph.D. is currently working at Pfizer in
Groton, CT, where she has a postdoctoral position focusing
on drug transporters and absolute protein quantification
strategies.
Jed Lampe, Ph.D. has taken an Assistant Professor position at
University of Kansas Medical Center, Department of Pharmacology,
Toxicology, and Therapeutics. He and his new family are busy.
Catherine Ibarra Drendall, Ph.D. is an Assistant Professor of
Medicine at the Duke University Medical Center with research interests
in the biology of early mammary carcinogenesis and biomarker
development to predict breast cancer likelihood in high-risk women as
well as identify potential molecular targets of therapy. She is currently
funded by the Susan G. Komen for the Cure Foundation to investigate the
protein expression patterns in biospecimens of African-American and
Caucasian women at a high risk for estrogen receptor-negative breast
cancer.
Brenda Nieslanik Kelly, Ph.D. is an Associate Professor of Biology and
Chemistry at Gustavus Adolphus College in St. Peter, MN.
Doug Lu, Ph.D. is finishing up a postdoc at UCSD School of
Pharmacy.
Art Roberts, Ph.D., who previously used and developed advanced
NMR and computational methods to study drug-drug interactions in
human cytochromes P450 (CYPs) as a postdoc in the lab, is now
applying these methods at the University of California, San
Diego (UCSD) in the laboratory of Dr. James R. Halpert. He plans
to use this technology to study the drug transporter P-glycoprotein (P-gp)
and the drug-conjugating enzyme UDP glucuronosyltransferases (UGTs)
as a junior faculty member in the future.
Lisa Storch Goldberg, Ph.D. resides
in Seattle with her husband
and two daughters. She divides
her time between raising her
children, developing an introduction
to science program for preschoolers,
and tutoring chemistry.
RESEARCH INTERESTS
TECHNIQUES AND INSTRUMENTS
We use a wide variety of spectroscopic and analytical techniques
in the course of our research. We own a Fluorolog Tau-3 frequency-domain
instrument for time-resolved fluorimetry, as well as two SLM/Aminco steady-state
fluorimeters (an AB-2 and an 8100) and an Applied Photophysics
SX.18MV-R for stopped-flow fluorescence and absorbance measurements. We
also own two Waters HPLC systems for analytical and preparative purposes.
We share a number of instruments with the rest of the Medicinal Chemistry Department,
including a Varian 500 MHz Unity Inova NMR, absorbance spectrophotometers (an
Olis Modernized Aminco DW-2 and a Cary 3E), and facilities for protein
expression in bacterial and insect-cell systems.
We have access to several mass spectrometry instruments via the Department's
Mass Spectrometry
Center, as well as several additional NMR instruments (a 750 MHz, a 500 MHz,
and two 300 MHz) via the
Dept. of Chemistry NMR facility. For surface plasmon resonance experiments, we use a
Biacore 2000 in the
Dept. of Physiology & Biophysics, and we also have access
to nanoscale characterization and fabrication tools (atomic force microscopy, electron
microscopy and confocal fluorescence microscopy) at the
Nanotech User Facility and
the Dept. of Pathology
Electron Microscopy Center.
USEFUL LINKS
DATABASE & LIBRARY SEARCHES (UW restricted)
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