The Zalatan research group seeks to understand and engineer biochemical networks, with a focus on cell signaling, gene expression, and enzymatic biosynthesis. Our basic research efforts focus on the mechanisms that regulate specificity in interconnected cell signaling networks. Our engineering projects span a broad range of topics including metabolic engineering, enzymatic biosynthesis, and CRISPR-Cas tools to regulate gene expression in bacterial and eukaryotic systems.
These efforts will help us to understand how cells exert precise spatial and temporal control over biochemical reactions and provide us with new strategies to engineer biological functions. We use a combination of approaches from biochemistry, enzymology, and synthetic biology.
