Publications

NDRG investigators, led by Alec Smith, in collaboration with Curi Bio, have just published a study creating engineered neuromuscular junctions from human induced pluripotent stem cells. Our platform enables simultaneous measurement of neuromuscular junction function across 24 engineered tissues! We’re now working with industry leaders to use this system as a means to remove animal testing from the development of botox products that are widely used in both the medical and cosmetic fields.

https://www.sciencedirect.com/science/article/pii/S2666027X25000040?via%3Dihub#f0025

Changho Chun is lead author of a paper that was just accepted for publication in the Journal of Neuroscience.

Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure reveals that exposure of motor neurons to interferon-γ promotes cytoplasmic mis-localization of TDP-43 protein – a hallmark of ALS.