NDRG Team Reports a Novel System for Monitoring Skeletal Muscle Contraction Employing Magnetic Sensing of 3D engineered muscles

Publications / /

Smith AS, Luttrell SM, Dupont J-B, Gray K, Lih D, Fleming JW, Cunningham NJ, Jepson S, Hesson J, Mathieu J, Maves L, Berry BJ, Fisher EC, Sniadecki NJ, Geisse NA & Mack DL (2022) High-throughput, real-time monitoring of engineered skeletal muscle function using magnetic sensing. J. Tissue Eng. 13, 20417314221122130

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Alec Smith awarded NIH R03 grant

Grants / /

Alec Smith has been awarded a two-year R03 grant from NIH entitled Using functional readouts from engineering models of innervated skeletal muscle to assess the efficacy of CRISPR-based c9orf72 ALS gene therapies.

This project is part of a larger effort to employ human induced pluripotent stem cell-derived motor neurons and skeletal muscle to produce in vitro models of the neuromuscular junction to model motor neuron diseases in order to study disease mechanisms and for drug screens.

Alec Smith awarded NIH R03 grant Read More »