April 22, 2024

Enterics for Global Health Consortium publishes a protocol supplement describing the study rationale and methods

Sixteen articles authored by the Enterics for Global Health (EFGH) Shigella surveillance study Consortium were recently published in the March 2024 issue of Open Forum Infectious Diseases.

The Enterics for Global Health (EFGH) Shigella surveillance study is a multi-country diarrhea surveillance study that aims to generate key data to optimize the design and implementation of pivotal Shigella vaccine trials. The protocol supplement describes the study rationale and current Shigella vaccine landscape, Consortium governance structure, epidemiologic and laboratory methods, and country site descriptions (Bangladesh, The Gambia, Kenya, Malawi, Mali, Pakistan, and Peru).

The EFGH study’s grant funding supported a planning phase from 2021-2022 that enabled protected time for EFGH Consortium investigators to co-develop the study protocol, standard operating procedures, develop training materials, and establish shared goals and a strong scientific foundation to facilitate collaborative engagement.  The protocol supplement underscores the EFGH Consortium’s priorities of advancing responsible and equitable research partnerships, equitable authorship practices, shared decision making, as well as early career investigator mentorship programs centered on partner-identified training and capacity building priorities.

The supplement introduction highlights the Rising Star Seed Award and Manuscript Writing Certificate Programs, administered by Global WACh consortium members, designed to provide structured training and mentorship support to early career researchers within the consortium using already collected data from the study.