Alliance for Pandemic Preparedness

September 28, 2020

Risk Factors Associated with Adverse Fetal Outcomes in Pregnancies Affected by Coronavirus Disease 2019 (COVID-19): A Secondary Analysis of the WAPM Study on COVID-19

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  • The risk of vertical transmission of SARS-CoV-2 was very low in a multinational cohort of 250 neonates born to pregnant women with COVID-19, with only 1 infant (0.4%) testing positive by RT-PCR of pharyngeal swabs performed after delivery. The infant who tested positive was asymptomatic and had a negative RT-PCR test after 14 days of life. Overall, 7% experienced a composite adverse fetal outcome (6 miscarriage, 10 with intrauterine growth restriction, and 5 neonatal death).

Di Mascio et al. (Sept 25, 2020). Risk Factors Associated with Adverse Fetal Outcomes in Pregnancies Affected by Coronavirus Disease 2019 (COVID-19): A Secondary Analysis of the WAPM Study on COVID-19. Journal of Perinatal Medicine. https://doi.org/10.1515/jpm-2020-0355