October 6, 2020

Association of Smoking Status with Outcomes in Hospitalised Patients with COVID-19

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): risk factors

• Analysis of a large retrospective study (n=1,137) found that among adults hospitalized with COVID-19, smokers were more likely to develop critical illness that required mechanical ventilation (47% vs 37%, p=0.005). In univariate analysis, current smokers had a 1.6-fold higher risk of death compared with never smokers (95% CI: 1.2-2.1). In adjusting for confounders, female sex, young age, low serum lactate dehydrogenase, and systemic steroid use were all associated with improved survival.

Adrish et al. (Oct 5, 2020). Association of Smoking Status with Outcomes in Hospitalised Patients with COVID-19. BMJ Open Respiratory Research. https://doi.org/10.1136/bmjresp-2020-000716