Alliance for Pandemic Preparedness

October 6, 2020

Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

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Geographic Spread

  • Genomic analysis of 6,359 SARS-CoV-2 isolates from the US identified a pattern of strongly localized outbreaks, which may point to the effectiveness of travel restriction policies and other public health measures. The authors identified prominent trends of localized haplotype patterns, which are the collection of variants in a viral genome, particular to Washington and California as well as other states.

Shen et al. (Sept 3, 2020). Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2020.573430