Alliance for Pandemic Preparedness

October 26, 2020

Seropositive Prevalence of Antibodies Against SARS-CoV-2 in Wuhan, China

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A cross-sectional study of healthy adults in Wuhan, China (n=35,040) with no prior history of COVID-19 found that the seroprevalence was 3.9% among the study population in samples taken eight weeks following the peak infection period. Most individuals tested positive for SARS-CoV-2 IgG antibodies only, indicating previous infection. Seropositive prevalence was higher in urban areas than rural or suburban areas (4.4% vs 2.9%), and higher in women than men (4.4% vs 3.3%). It was also significantly higher among elderly individuals (9.2%) compared with other age groups.

Liu et al. (Oct 23, 2020). Seropositive Prevalence of Antibodies Against SARS-CoV-2 in Wuhan, China. JAMA Network Open. https://doi.org/10.1001/jamanetworkopen.2020.25717