Alliance for Pandemic Preparedness

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Tag: seroprevalence

April 12, 2021

Seroprevalence of SARS-CoV-2 Following the Largest Initial Epidemic Wave in the United States: Findings from New York City, May 13-July 21, 2020

In a serosurvey of 45,367 New York City adult residents, 23.6% were infected with SARS-CoV-2 during the first few months of the pandemic (May 13 – July 21, 2020). High seroprevalence (>30%) was observed among Black and Hispanic individuals, people from high poverty neighborhoods, and people in health care or essential worker industry sectors. Reporting…

November 19, 2020

Global Seroprevalence of SARS-CoV-2 Antibodies a Systematic Review and Meta-Analysis

[Pre-print, not peer reviewed] In a systematic review and meta-analysis of 338 seroprevalence studies representing 50 countries and 2.3 million participants, global SARS-CoV-2 seroprevalence in the general population was low (median 3.2%, IQR 1.0-6.4%) through August 2020, suggesting that most of the population still remains susceptible to infection. Seroprevalence was higher among Black and Asian…

November 5, 2020

Repeated Cross-Sectional Sero-Monitoring of SARS-CoV-2 in New York City

Repeat cross-sectional serosurveys conducted from February to July of residual clinical samples from two patient groups in a New York Hospital — 1) an urgent care (UC) group, enriched with COVID-19 cases, and 2) a routine care (RC) group, which resembles the general population — identified seropositive samples from mid-February, though the first case of…

Household Transmission of SARS-COV-2 Insights from a Population-Based Serological Survey

[Pre-print, not peer-reviewed] A household serological survey conducted in Geneva from April to June (n=2,267 households) estimated a 17.2% risk of being infected with SARS-CoV-2 by a single household member compared to a 5.1% cumulative infection risk (through June 30th) from exposures outside the household. Infection risk from an infected household member increased with age,…

October 26, 2020

Seropositive Prevalence of Antibodies Against SARS-CoV-2 in Wuhan, China

A cross-sectional study of healthy adults in Wuhan, China (n=35,040) with no prior history of COVID-19 found that the seroprevalence was 3.9% among the study population in samples taken eight weeks following the peak infection period. Most individuals tested positive for SARS-CoV-2 IgG antibodies only, indicating previous infection. Seropositive prevalence was higher in urban areas…

October 13, 2020

Estimated Seroprevalence of SARS-CoV-2 Antibodies Among Adults in Orange County California

[Pre-print, not peer-reviewed] A SARS-CoV-2 surveillance study in Orange County, CA conducted from July to August 2020 reported an adjusted SARS-CoV-2 seroprevalence estimate of 11.5%, which is 7-fold greater than the estimate using official County statistics on cases reported. To minimize bias, the authors recruited adults (n=2,979) to answer a survey without knowing they would…