November 18, 2020

Characteristics of Pediatric Multi-System Inflammatory Syndrome (PMIS) Associated with COVID-19: A Meta-Analysis and Insights into Pathogenesis

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): children, clinical characteristics

A meta-analysis of pediatric multisystem inflammation syndrome (PMIS) documented three common types of PMIS clinical presentation: persistent fever and gastrointestinal symptoms, cardiogenic shock, and Kawasaki disease-like syndrome. In 7 studies including 182 patients, only 9% of patients presented with respiratory symptoms and only 37% were positive for SARS-CoV2 by PCR, while 81% were positive for antibodies against SARS-CoV-2. 

Zou et al. (Nov 9, 2020). Characteristics of Pediatric Multi-System Inflammatory Syndrome (PMIS) Associated with COVID-19: A Meta-Analysis and Insights into Pathogenesis. International Journal of Infectious Diseases. https://doi.org/10.1016/j.ijid.2020.11.145