Alliance for Pandemic Preparedness

November 19, 2020

Global Seroprevalence of SARS-CoV-2 Antibodies a Systematic Review and Meta-Analysis

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  • [Pre-print, not peer reviewed] In a systematic review and meta-analysis of 338 seroprevalence studies representing 50 countries and 2.3 million participants, global SARS-CoV-2 seroprevalence in the general population was low (median 3.2%, IQR 1.0-6.4%) through August 2020, suggesting that most of the population still remains susceptible to infection. Seroprevalence was higher among Black and Asian people than white people. Older age (65 years or older) and being a health worker were associated with higher seroprevalence. National seroprevalence estimates were 11.9 times higher than corresponding SARS-CoV-2 cumulative incidence.

Bobrovitz et al. (Nov 18, 2020). Global Seroprevalence of SARS-CoV-2 Antibodies a Systematic Review and Meta-Analysis. Pre-print downloaded Nov 19 from https://doi.org/10.1101/2020.11.17.20233460