Alliance for Pandemic Preparedness

November 19, 2020

SARS-CoV-2 Epidemic after Social and Economic Reopening in Three US States Reveals Shifts in Age Structure and Clinical Characteristics

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  • [Pre-print, not peer reviewed] Analysis of epidemic characteristics during and after lockdowns from Rhode Island, Massachusetts, and Pennsylvania – states that successfully reopened in May 2020 without subsequent summer waves – showed changes in age-dependent mixing patterns. Using several daily data streams and mobility data, population-average mixing rates dropped by >50% during lockdown. However, elderly individuals were less able to reduce contacts during lockdown than younger individuals, which potentially led to concentrated outbreaks among elderly congregate settings.

Wikle et al. (Nov 18, 2020). SARS-CoV-2 Epidemic after Social and Economic Reopening in Three US States Reveals Shifts in Age Structure and Clinical Characteristics. Pre-print downloaded Nov 19 from https://doi.org/10.1101/2020.11.17.20232918