November 20, 2020

Clinical Outcomes Of A COVID-19 Vaccine: Implementation Over Efficacy

Category: Article Summary

Topic: Modeling and Prediction

Keywords (Tags): modeling prediction, public health, summary

• A mathematical model used to estimate the population benefits of a vaccine against COVID-19 finds that factors related to implementation will contribute more to the success of vaccination programs than a vaccine’s efficacy as determined in clinical trials. The model suggests the benefits of a vaccine will decline substantially in the event of manufacturing or deployment delays, significant vaccine hesitancy, or greater epidemic severity.

Paltiel et al. (Nov 19, 2020). Clinical Outcomes Of A COVID-19 Vaccine: Implementation Over Efficacy. Health Affairs. https://doi.org/10.1377/hlthaff.2020.02054