Alliance for Pandemic Preparedness

November 24, 2020

Catching a Resurgence Increase in SARS-CoV-2 Viral RNA Identified in Wastewater 48 Hours before COVID-19 Clinical Tests and 96 Hours before Hospitalizations

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[Pre-print, not peer reviewed] Surveillance for SARS-CoV-2 at wastewater facilities in Ottawa identified resurgence of positive cases and hospitalizations in late July 2020 with a 48-hour and 96- hour lead time, respectively. When daily percent positivity was being reported below 1%, increases of >400% in normalized SARS-CoV-2 RNA signal in wastewater were identified 48 hours before a >300% increases in cases was reported and 96 hours before a >160% increase in community hospitalizations. 

D’Aoust et al. (Nov 23, 2020). Catching a Resurgence Increase in SARS-CoV-2 Viral RNA Identified in Wastewater 48 Hours before COVID-19 Clinical Tests and 96 Hours before Hospitalizations. Pre-print downloaded Nov 24 from https://doi.org/10.1101/2020.11.22.20236554