November 30, 2020

Are Psychiatric Disorders Risk Factors for COVID-19 Susceptibility and Severity: A Two-Sample Bidirectional Univariable and Multivariable Mendelian Randomization Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): risk factors

[Pre-print, not peer-reviewed] An analysis of potential bidirectional relationships between neuropsychiatric disorders and COVID-19 showed that genetic liability to bipolar disorder slightly increased COVID-19 susceptibility and severity, and there was no consistent evidence of COVID-19 influencing risk of developing psychiatric disorders. A combination of bipolar disorder and schizophrenia was associated with greater risk of contracting SARS-CoV-2 in a univariable Mendelian randomization analysis. 

Luykx et al. (Nov 30, 2020). Are Psychiatric Disorders Risk Factors for COVID-19 Susceptibility and Severity: A Two-Sample Bidirectional Univariable and Multivariable Mendelian Randomization Study. Pre-print downloaded Nov. 30 from https://doi.org/10.1101/2020.11.29.20240481