Alliance for Pandemic Preparedness

December 30, 2020

Previous Dengue Infection and Mortality in COVID-19

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In a prospective study of 2,351 people with COVID-19 SARS in Brazil, those with previous symptomatic dengue (n=1177) had a lower risk of death after a median follow-up of 60 days (adjusted HR = 0.44). History of other previous infections, including malaria, Zika, and chikungunya, were not associated with mortality. The authors suggest that dengue might induce a degree of immunological protection against SARS-CoV-2 infection.

Silvestre et al. (Dec 29, 2020). Previous Dengue Infection and Mortality in COVID-19. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1895