January 4, 2021

Mortality in Hospitalized Patients with Cancer and Coronavirus Disease 2019: A Systematic Review and Meta‐analysis of Cohort Studies

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): risk factors

A systematic review and meta-analysis of the effects of COVID-19 on the clinical outcomes of patients with cancer indicated that the pooled 30‐day mortality rate from 13 primarily inpatient studies (n=2922 patients) was 30%. The overall pooled 30‐day mortality risk from 5 studies that included a mixture of inpatient and outpatient populations (n=624 patients) was 15%, and there was significant heterogeneity across studies. In multivariable metaregression, male sex, along with an interaction between the median patient age and recent active cancer therapy, explained most of the between‐study heterogeneity (R²=96%).

Desai et al. (Dec 30, 2020). Mortality in Hospitalized Patients with Cancer and Coronavirus Disease 2019: A Systematic Review and Meta‐analysis of Cohort Studies. Cancer. https://doi.org/10.1002/cncr.33386