January 27, 2021

SARS-CoV-2 Serology Levels in Pregnant Women and Their Neonates

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): immunity, pregnancy

A study of the serologic response to SARS-CoV-2 infection in pregnant women (n = 88) found that asymptomatic pregnant women mounted a lower immune response than symptomatic pregnant women, and that maternal IgG antibodies were positively correlated with levels in neonates. Maternal IgM and IgG levels peaked around 15 and 30 days after onset of symptoms, respectively. Passive transfer of IgG was identified in 78% of all neonates. 

Kubiak et al. (Jan 2021). SARS-CoV-2 Serology Levels in Pregnant Women and Their Neonates. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/j.ajog.2021.01.016