Alliance for Pandemic Preparedness

January 28, 2021

Disease Severity, Pregnancy Outcomes and Maternal Deaths among Pregnant Patients with SARS-CoV-2 Infection in Washington State

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Among a cohort of 240 pregnant patients with SARS-CoV-2 infection in Washington State, the COVID-19 hospitalization and case fatality rates were 3.5-fold and 13.6-fold higher, respectively, compared to rates among similarly-aged females and males with SARS-CoV-2 infections in Washington State.  One in 11 developed severe or critical disease, 1 in 10 were hospitalized for COVID-19. Patients who were hospitalized were slightly older (median 32 vs. 28 years) and more likely to have at least one comorbidity (45.8% vs 17.6%) than those who were not hospitalized. Three maternal deaths from COVID-19 were reported, corresponding to a maternal mortality rate of 1,250 per 100,000 pregnancies and a 1.2% absolute rate difference compared to similarly-aged adults.

Lokken et al. (Jan 26, 2021). Disease Severity, Pregnancy Outcomes and Maternal Deaths among Pregnant Patients with SARS-CoV-2 Infection in Washington State. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/j.ajog.2020.12.1221