January 28, 2021

Quantifying the Transmission Advantage Associated with N501Y Substitution of SARS-CoV-2 in the United Kingdom: An Early Data-Driven Analysis

Category: Article Summary

Topic: Transmission

Keywords (Tags): transmission, variants

Using publicly available SARS-CoV-2 sequencing data and COVID-19 surveillance data collected from August to December 2020 in the UK, Zhao et al. reconstructed the variant-specific instantaneous reproduction number, Rt, and estimated that the variant containing the N501Y mutation is 52% more transmissible than the wild-type virus.

Zhao et al. (Jan 28, 2021). Quantifying the Transmission Advantage Associated with N501Y Substitution of SARS-CoV-2 in the United Kingdom: An Early Data-Driven Analysis. Journal of Travel Medicine. https://doi.org/10.1093/jtm/taab011