February 2, 2021

Genetically Predicted Serum Vitamin D and COVID-19 a Mendelian Randomization Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): risk factors

[Pre-print, not peer reviewed] Long-term vitamin D nutritional status does not causally affect susceptibility to SARS-CoV-2 infection or more severe COVID-19 disease course, according to a two-sample Mendelian randomization study of a European cohort. No elevation in the risk of COVID infection, hospitalization, or progression to severe COVID-19 was associated with serum vitamin D status in the cohort of 18,000 COVID-19 cases and 1.4 million controls from the UK Biobank and SUNLIGHT Consortium that used single nucleotide polymorphisms to predict differences in long-term serum vitamin D levels. 

Patchen et al. (Feb 1, 2021). Genetically Predicted Serum Vitamin D and COVID-19 a Mendelian Randomization Study. Pre-print downloaded Feb 2 from https://doi.org/10.1101/2021.01.29.21250759