Alliance for Pandemic Preparedness

February 4, 2021

Epidemiological and Evolutionary Considerations of SARS-CoV-2 Vaccine Dosing Regimes

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[Pre-print, not peer reviewed] An immuno-epidemiological model suggests that a one-dose vaccination strategy would likely decrease SARS-CoV-2 infections, but only in the short term. Long-term outcomes, as well as likelihood of viral evolution driven by partial immunity, are mainly driven by relative immune robustness of one versus two doses.

Saad-Roy et al. (Feb 3, 2021). Epidemiological and Evolutionary Considerations of SARS-CoV-2 Vaccine Dosing Regimes. Pre-print downloaded Feb 4 from https://doi.org/10.1101/2021.02.01.21250944