February 22, 2021

Increased Hazard of Mortality in Cases Compatible with SARS-CoV-2 Variant of Concern 2020121 – a Matched Cohort Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): mortality, variants

[Pre-print, not peer-reviewed] Findings from a cohort study among people tested for SARS-CoV-2 in community settings in the UK suggest the SARS-CoV-2 B.1.1.7 variant strain is associated with a higher risk of mortality. The hazard ratio for mortality was 1.7 for the variant strain compared to infection with previously circulating strains. This represents an increase in deaths from 1.8 to 3.1 in 1000 detected cases.

Challen et al. (Feb 19, 2021). Increased Hazard of Mortality in Cases Compatible with SARS-CoV-2 Variant of Concern 2020121 – a Matched Cohort Study. Pre-print downloaded Feb 22 from https://doi.org/10.1101/2021.02.09.21250937