Alliance for Pandemic Preparedness

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Tag: mortality


June 15, 2021

Estimation of Excess Mortality Rates Among US Assisted Living Residents During the COVID-19 Pandemic

Incidence of all-cause mortality among a cohort of US Medicare beneficiaries residing in assisted living settings between January to August 2020 (n=425,333) was 17% higher compared to a cohort from the same time in 2019 (n=422,262). The incidence ratio was 36% higher during the peak week in April 8-14, 2020 (3.3 vs 2.2 deaths per…


May 21, 2021

Excess Deaths Associated with Covid-19 Pandemic in 2020: Age and Sex Disaggregated Time Series Analysis in 29 High Income Countries

A time series study of excess deaths in 29 high income countries (including the US) found that nearly 1 million excess deaths occurred in 2020. These excess deaths exceed officially reported deaths from COVID-19 in many countries, suggesting that analysis of excess deaths is needed to determine the full impact of the pandemic on mortality….


April 27, 2021

6-Month Follow Up of 8679 Hospitalized COVID-19 Patients in Germany A Nationwide Cohort Study

[Pre-print, not peer-reviewed] 180-day mortality was 30% in a large cohort (n=8,679; median age 72 years) from Germany hospitalized with COVID-19 from February to April 2020. 180-day mortality was 52% among patients aged ≥80 years and 53% for patients who had undergone invasive mechanical ventilation. Coagulopathy, BMI ≥ 40, and age were risk factors for…


April 23, 2021

The Global Case-Fatality Rate of COVID-19 Has Been Declining Since May 2020

A retrospective evaluation of WHO SARS-CoV-2 daily situation reports data found that the global cumulative reported case fatality rate (rCFR) reached a peak of 7.2% during the week of April 22-28, 2020 before declining to 2.2% in December 28-31, 2020. The decline in rCFR was not associated with an increase in tests performed. However, county-level…


April 16, 2021

Notes from the Field: Update on Excess Deaths Associated with the COVID-19 Pandemic — United States, January 26, 2020–February 27, 2021

An estimated 545,600 to 660,200 excess deaths occurred in the US during January 2020 to February 2021 according to data from the National Vital Statistics System (NVSS). Excess deaths peaked during the weeks ending April 11, 2020, August 1, 2020, and January 2, 2021. Approximately 75-88% of excess deaths were directly associated with COVID-19. Excess…


April 6, 2021

Estimates and Projections of COVID-19 and Parental Death in the US

An estimated 37,300 children aged 0-17 years in the US had lost at least 1 parent due to COVID-19 by February 2021, of which roughly 3 in 4 are adolescents aged 10-17 years. Estimates were computed by taking current COVID-19 mortality estimates (479,000) and applying a bereavement multiplier (number of children parentally bereaved per COVID-19…


April 5, 2021

Excess Deaths From COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021

The US experienced 22.9% more deaths than expected (522,368 excess deaths) between March 1, 2020 and January 2, 2021. The rate of excess deaths was higher among non-Hispanic Black (208.4 deaths per 100 000) than non-Hispanic white or Hispanic populations (157.0 and 139.8 deaths per 100 000, respectively); these groups accounted for 16.9%, 61.1%, and 16.7% of…


April 1, 2021

Death Certificate–Based ICD-10 Diagnosis Codes for COVID-19 Mortality Surveillance — United States, January–December 2020

The number of US death certificates from 2020 listing COVID-19 and at least one other co-occurring diagnosis were consistent with the number of deaths attributable to COVID-19 in 2020 (approximately 375,000) reported to the CDC’s National Vital Statistics System (NVSS). Among 378,048 death certificates including the ICD-10 code for COVID-19, 5.5% (20,915) only listed that…


March 9, 2021

Elevated Mortality among People Experiencing Homelessness with COVID-19

[Pre-print, not peer-reviewed] The COVID-19 case fatality rate (CFR) among people experiencing homelessness (PEH) residing in 7 of the most populous US health jurisdictions was 1.3-times higher than that of the general population. In Los Angeles County, where PEH data is further stratified by additional demographic characteristics, the PEH CFR was up to 14-times higher…


Case Fatality Risk of the SARS-CoV-2 Variant of Concern B.1.1.7 in England

[Pre-print, not peer-reviewed] Infection with the SARS-CoV-2 B.1.1.7 variant was associated with 1.7-fold increased risk of death compared to infection with non-B.1.1.7 strains, according to UK electronic health record data collected from November 2020 to February 2021. Increased risk of death was consistent across subgroups by age, number of comorbidities, ethnicity, and deprivation index quintile….



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