Alliance for Pandemic Preparedness

March 3, 2021

Persistent SARS-CoV-2 RNA Shedding without Evidence of Infectiousness: A Cohort Study of Individuals with COVID-19

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  • A study of SARS-CoV-2 viral shedding showed that while most (97%) of people with mild to moderate COVID-19 continue to shed viral RNA for more than 10 days after symptom onset, virus could not be recovered by cell culture in any of the 35 individuals sampled more than 10 days after symptom onset. The authors conclude that this provides some evidence that individuals with mild to moderate COVID-19 are less likely to be infectious ≥10 days after symptom onset.

Owusu et al. (Feb 27, 2021). Persistent SARS-CoV-2 RNA Shedding without Evidence of Infectiousness: A Cohort Study of Individuals with COVID-19. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiab107