Alliance for Pandemic Preparedness

March 31, 2021

Role of High-Dose Exposure in Transmission Hot Zones as a Driver of SARS-CoV-2 Dynamics

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  • A model of SARS-CoV-2 transmission found that community spread may be highly influenced by transmission within “hot zones” characterized by high viral dose exposure, such as indoor settings with poor ventilation such as long-term care facilities, prisons, and food processing plants. The authors conclude that this may indicate that targeting interventions to prevent transmission in hot zones may suppress spread throughout the general population. They suggest that this may allow for fewer non-pharmaceutical interventions in the community at large.

Wodarz et al. (Mar 2021). Role of High-Dose Exposure in Transmission Hot Zones as a Driver of SARS-CoV-2 Dynamics. Journal of the Royal Society, Interface. https://doi.org/10.1098/rsif.2020.0916