Alliance for Pandemic Preparedness

April 20, 2021

Multisystem Inflammatory Syndrome in Infants <12 Months of Age, United States, May 2020–January 2021

Category:

Topic:

Keywords (Tags): ,

  • A total of 83 of 85 (98%) of infants aged <12 months with multisystem inflammatory syndrome (MIS-C) tested positive for SARS-CoV-2 by either PCR or serology, according to data from a US surveillance system from May 2020 to January 2021. Rash, diarrhea, and vomiting were the most common reported symptoms and the median time from symptom onset to hospitalization was three days. Median time to recovery was four days. One infant with complex congenital malformations died after experiencing multisystem organ failure secondary to MIS-C.  

Godfred-Cato et al. (Apr 16, 2021). Multisystem Inflammatory Syndrome in Infants <12 Months of Age, United States, May 2020–January 2021. Pediatric Infectious Disease Journal. https://doi.org/10.1097/INF.0000000000003149