Alliance for Pandemic Preparedness

Result for
Tag: infant

April 29, 2021

Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes

SARS-CoV-2 infection in pregnancy (from conception to 1 week after birth) was significantly associated with a 1.4-fold higher risk of any neonatal respiratory disorder after matching for maternal characteristics in a nationwide cohort study in Sweden (n=88,159 infants). Admission for neonatal care, respiratory distress syndrome, and hyperbilirubinemia were also associated with maternal SARS-CoV-2 test positivity….

Maternal Antibody Response, Neutralizing Potency, and Placental Antibody Transfer After Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) Infection

Among maternal blood samples from SARS-CoV-2 positive patients obtained after delivery (n=32), higher median anti-RBD IgG titers were significantly associated with symptomatic (vs. asymptomatic) infection but not with having a PCR-positive test more than 14 days earlier (vs. PCR-positive test within 14 days). Paired cord blood samples also obtained after delivery show that median cord/maternal…

April 20, 2021

Multisystem Inflammatory Syndrome in Infants <12 Months of Age, United States, May 2020–January 2021

A total of 83 of 85 (98%) of infants aged <12 months with multisystem inflammatory syndrome (MIS-C) tested positive for SARS-CoV-2 by either PCR or serology, according to data from a US surveillance system from May 2020 to January 2021. Rash, diarrhea, and vomiting were the most common reported symptoms and the median time from…

March 9, 2021

COVID-19 Vaccine Response in Pregnant and Lactating Women a Cohort Study

[Pre-print, not peer-reviewed] The Pfizer-BioNTech and Moderna vaccines elicited similar immune responses among pregnant (n=84) and lactating (n=31) women compared to non-pregnant reproductive-age women (n=16). All vaccine-induced SARS-CoV-2-specific antibody titers were higher compared to titers from a group of pregnant women (n=37) that had SARS-CoV-2 infection 4-12 weeks prior. Vaccine-induced antibodies were detected in all…

November 18, 2020

Singleton Preterm Birth Rates for Racial and Ethnic Groups during the Coronavirus Disease 2019 Pandemic in California

In California, the lockdown in response to the COVID-19 pandemic was not associated with changes in the overall rate of pre-term birth (<37 weeks), although there was an increase in the rate of birth at less than 32 weeks. During a 4-month period following the state-wide COVID-19 lockdown in California in March, 2020, there was…