April 21, 2021

The Risk of Symptomatic Reinfection during the Second COVID-19 Wave in Individuals Previously Exposed to SARS-CoV-2

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): re-infection

• [Pre-print, not peer-reviewed] In a cohort study in Italy, the adjusted odds ratio for developing symptomatic SARS-CoV-2 infection with SARS-CoV-2 IgG antibodies was 0.05 in the six months following antibody measurement when compared to individuals who were seronegative. The cumulative incidence of laboratory-confirmed, symptomatic infections among IgG-negative and IgG positive cohorts was 2.7% in seronegative individuals and 0.14% in seropositive individuals, respectively. 

Manica et al. (Apr 20, 2021). The Risk of Symptomatic Reinfection during the Second COVID-19 Wave in Individuals Previously Exposed to SARS-CoV-2. Pre-print downloaded Apr 21 from https://doi.org/10.1101/2021.04.14.21255502