April 22, 2021

Preliminary Findings of MRNA Covid-19 Vaccine Safety in Pregnant Persons

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): pregnancy, vaccines

• Among women in the V-safe pregnancy registry who reported completing pregnancy after receiving COVID-19 mRNA vaccines (Pfizer-BioNTech or Moderna) from December to February 201 (n=827), adverse pregnancy and neonatal outcomes occurred in similar proportions as previously studies of pregnant women conducted before the COVID-19 pandemic. 14% resulted in pregnancy loss, 86% resulted in live birth (most among those vaccinated during their third trimester). Preterm birth occurred in 9.4% and small size for gestational age in 3.2%. No neonatal deaths were reported. 

Shimabukuro et al. (Apr 21, 2021). Preliminary Findings of MRNA Covid-19 Vaccine Safety in Pregnant Persons. New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2104983