Alliance for Pandemic Preparedness

May 3, 2021

Household Clustering of SARS-CoV-2 Variant of Concern B.1.1.7 (VOC-202012-01) in England

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  • In a study in England of all sequenced positive SARS-CoV-2 test results between October 1 – December 15, 2020, odds of household clustering with the SARS-CoV-2 B.1.1.7 variant was 1.9-fold higher than with wildtype virus, after adjusting for Index of Multiple Deprivation, region of residence, time of testing, age group, sex, race, and ethnicity of the index case. Household clusters were defined as a sequenced index case followed by one or more laboratory confirmed SARS-CoV-2 cases at the same private dwelling unit within 14 days. Higher odds of clustering were found in less deprived households and lower odds when the index case was age 70 years or older.

Chudasama et al. (Apr 2021). Household Clustering of SARS-CoV-2 Variant of Concern B.1.1.7 (VOC-202012-01) in England. Journal of Infection. https://doi.org/10.1016/j.jinf.2021.04.029