Alliance for Pandemic Preparedness

May 3, 2021

Quality-Adjusted Life-Year Losses Averted With Every COVID-19 Infection Prevented in the United States

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  • Averting one SARS-CoV-2 infection among a representative US resident would generate an additional 0.061 quality-adjusted life-years (QALYs) (0.055 for the patient; 0.006 for the patient’s family members) according to a probabilistic simulation model informed by CDC COVID-19 estimates.  Preventing one infection would result in a total of 1.51 total QALYs gained over a longer time horizon of 15 months if the ongoing transmission from the index patient is included, though the analysis assumes that an effective vaccine is not available until three months into the simulation.  

Basu and Gandhay. (May 2021). Quality-Adjusted Life-Year Losses Averted With Every COVID-19 Infection Prevented in the United States. Value in Health. https://doi.org/10.1016/j.jval.2020.11.013