May 21, 2021

Persistence of SARS-CoV-2-Specific IgG in Children 6 Months After Infection, Australia

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): children, immunity

• A longitudinal cohort study of Australian adults (N=32) and children (N=22) with SARS-CoV-2 infection who were asymptomatic or had mild symptoms detected similar levels of specific IgG antibodies 6 months after infection in both children and adults. There was no significant difference in geometric mean antibody concentration from 43 to 195 days after infection, suggesting durable humoral immune response. The authors caution that these results do not include other components of immune response such as cellular and mucosal immunity.  

Toh et al. (May 2021). Persistence of SARS-CoV-2-Specific IgG in Children 6 Months After Infection, Australia. Emerging Infectious Diseases. https://wwwnc.cdc.gov/eid/article/27/8/21-0965_article