June 2, 2021

Stopping the Misinformation BNT16b2 COVID-19 Vaccine Has No Negative Effect on Women’s Fertility

Category: Article Summary

Topic: Vaccines and Immunity

Keywords (Tags): pregnancy, vaccines

• [Pre-print, not peer-reviewed] A study of 47 women undergoing in vitro fertilization (IVF) in Israel found no significant differences in IVF cycle outcomes in all participants prior to and after receiving the Pfizer-BioNTech vaccine, suggesting that vaccination has no negative effect on fertility using assisted reproductive technology. No significant differences were observed in the number of oocytes received, number of mature oocytes, and fertilization rate when comparing individual woman before and after vaccination (each participant served as their own control). In addition, no significant differences in embryo parameters were observed. In a subset of participants (n=15), there were no significant differences in the number or percentage of clinical pregnancies. To account for effects of sperm on fertilization, only patients undergoing intracytoplasmic sperm injection, a process where a single sperm is injected into a mature egg, were considered.

Safrai et al. (June 1, 2021). Stopping the Misinformation BNT16b2 COVID-19 Vaccine Has No Negative Effect on Women’s Fertility. Pre-print downloaded Jun 2 from https://doi.org/10.1101/2021.05.30.21258079