June 14, 2021

International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): children, clinical characteristics

• A cohort study of children and adolescents (n=671) from France, Germany, Spain, Singapore, the UK, and the US found varying trends in COVID-19 hospitalizations and complications between countries, with hospitalizations in the cohort mirroring those of national-level pediatric hospitalization trends for most countries with available data. Laboratory values for 16 assays were analyzed, which indicated elevated levels of inflammatory markers, including C-reactive protein, ferritin, and procalcitonin. Common complications included cardiac arrhythmias (15%), viral pneumonia (13%), and respiratory failure (11%). Few children were treated with COVID-19–directed medications.

Bourgeois et al. (June 2021). International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries. JAMA Network Open. https://doi.org/10.1001/jamanetworkopen.2021.12596