June 14, 2021

Risk Factors for Hospitalization Disease Severity and Mortality in Children and Adolescents with COVID-19 Results from a Nationwide German Registry

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): children, clinical characteristics

• [Pre-print, not peer-reviewed] A cohort study of children and adolescents (n=1,501) who were admitted to the hospital between March 18, 2020 and April 30, 2021 in Germany and who tested positive for SARS-CoV-2 found that although approximately half of the cohort was not admitted to the hospital due to COVID-19, 72% had infection-related symptoms during hospitalization. Pre-existing conditions, including respiratory disorders, and neurological, neuromuscular, and cardiovascular diseases, were present in 28% of participants. In a fully adjusted model, patient age, trisomy 21, coinfections and primary immunodeficiencies were significantly associated with intensive care treatment. 

Armann et al. (June 13, 2021). Risk Factors for Hospitalization Disease Severity and Mortality in Children and Adolescents with COVID-19 Results from a Nationwide German Registry. Pre-print downloaded Jun 14 from https://doi.org/10.1101/2021.06.07.21258488