Alliance for Pandemic Preparedness

October 12, 2020

Age-Targeted Dose Allocation Can Halve COVID-19 Vaccine Requirements

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  • [Pre-print, not peer reviewed] An age-structured mathematical model investigating age-specific allocation strategies for SARS-CoV-2 vaccines indicated that across 179 countries, the highest priority individuals for vaccination were typically those 30-59 years of age, based on their higher risk of infection and disease, and greater rates of contact. The model assumed that the vaccine would be 70% effective, and that there was age-dependent susceptibility and disease severity. The authors estimate that optimizing how the COVID-19 vaccine is allocated can more than double its impact in reducing SARS-CoV-2 transmission for a fixed number of doses.

Meehan et al. (Oct 11, 2020). Age-Targeted Dose Allocation Can Halve COVID-19 Vaccine Requirements. Pre-print downloaded Oct 12 https://doi.org/10.1101/2020.10.08.20208108