October 13, 2020

enomic Evidence for Reinfection with SARS-CoV-2: A Case Study. The Lancet Infectious Diseases

Category: Article Summary

Topic: Transmission

Keywords (Tags): transmission

• A man in Nevada was found to be the first case of SARS-CoV-2 reinfection in North America, testing positive first in April, then receiving two negative tests during follow-up in May, then testing positive again in June. Genomic analysis of the positive samples show significant genetic differences between viral strains collected during the two periods that could not be accounted for by short-term in vivo evolution, suggesting the patient was infected on two separate occasions. The second infection was reported to be symptomatically more severe than the first. [EDITORIAL NOTE: This manuscript was previously summarized in the Lit Rep as a pre-print on August 31, 2020].

Tillett et al. (Oct 12, 2020). Genomic Evidence for Reinfection with SARS-CoV-2: A Case Study. The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(20)30764-7