Alliance for Pandemic Preparedness

November 5, 2020

Repeated Cross-Sectional Sero-Monitoring of SARS-CoV-2 in New York City

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  • Repeat cross-sectional serosurveys conducted from February to July of residual clinical samples from two patient groups in a New York Hospital — 1) an urgent care (UC) group, enriched with COVID-19 cases, and 2) a routine care (RC) group, which resembles the general population — identified seropositive samples from mid-February, though the first case of COVID-19 in New York City was not confirmed until March 1. Following peaks in March-April, seroprevalence then declined to slightly above 20% through July in both groups, which the authors note as significantly lower than what would be required for herd immunity.

Stadlbauer et al. (Nov 3, 2020). Repeated Cross-Sectional Sero-Monitoring of SARS-CoV-2 in New York City. Nature. https://doi.org/10.1038/s41586-020-2912-6