March 1, 2021

Exploratory Analysis of Immunization Records Highlights Decreased SARS-CoV-2 Rates in Individuals with Recent Non-COVID-19 Vaccinations

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): risk factors, vaccines

• An exploratory analysis of immunization records from the Mayo clinic found that receipt of multiple vaccines within the past five years were associated with protection from SARS-CoV-2 infection.  In an analysis of medical records from 137,037 individuals tested for SARS-CoV-2 by PCR , receipt of vaccines for polio, Haemophilus influenzae type-B (HIB), measles-mumps-rubella (MMR), Varicella, pneumococcal conjugate (PCV13), Geriatric Flu, and hepatitis A/hepatitis B (HepA–HepB) were associated with lower rates of SARS-CoV-2 infection. This relationship was maintained even after adjusting for geographic SARS-CoV-2 incidence and testing rates, demographics, comorbidities, and number of other vaccinations.  Receipt of another 11 vaccines (typhoid, tetanus, Zoster, rotavirus, PCV23, pediatric flu, meningiococcal, live influenza, general influenza, HPV, or geriatric flu) was not associated with SARS-CoV-2 infection. 

Pawlowski et al. (Dec 26, 2021). Exploratory Analysis of Immunization Records Highlights Decreased SARS-CoV-2 Rates in Individuals with Recent Non-COVID-19 Vaccinations. Scientific Reports. https://doi.org/10.1038/s41598-021-83641-y