Alliance for Pandemic Preparedness

May 24, 2021

Maternal and Perinatal Outcomes of Pregnant Women with SARS-CoV-2 Infection at the Time of Birth in England: National Cohort Study

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  • A population-based cohort study of pregnant persons in England (n = 342,080) in the context of universal screening for SARS-CoV-2 at delivery hospitalization found that SARS-CoV-2 infection was more common among those who were younger, of non-white ethnicity, pregnant for the first time, resided in the most deprived areas, or had comorbid conditions. Risk of fetal death (aOR = 2.2), preterm birth (aOR = 2.2), preeclampsia/eclampsia (aOR = 1.6), and emergency Cesarean delivery (aOR = 1.6) were all significantly higher among pregnant individuals infected with SARS-CoV-2. The observed increase in adverse fetal outcomes was attributed to increased risk of preterm birth.

GUROL-URGANCI et al. (May 2021). Maternal and Perinatal Outcomes of Pregnant Women with SARS-CoV-2 Infection at the Time of Birth in England: National Cohort Study. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/j.ajog.2021.05.016