Article Summary
November 5, 2020
Testing the waters: is it time to go back to school? Diagnostic screening as a COVID‐19 risk‐mitigation strategy for reopening schools in King County, WA
[Pre-print, not peer-reviewed] Modeling of K-12 school reopening in King County, Washington found that if in-school countermeasures are observed, diagnostic screening either with PCR tests or rapid antigen tests may be of little benefit due to a higher rate of false positive tests in this low prevalence setting. Modeled in-school countermeasures included daily symptom screening,…
Clinical Characteristics of Re-Positive COVID-19 Patients in Huangshi, China: A Retrospective Cohort Study
In an observational retrospective cohort study in Huangshi, China, 23 out of 368 recovered COVID-19 patients quarantined for 14 days post-discharge retested positive for SARS-CoV-2. Retesting positivity was associated with a higher ratio of lymphocytes on admission and presence of comorbidities, while negatively associated with a lower peak temperature during hospitalization and arbidol treatment. Zhou…
Lack of Antibodies to SARS-CoV-2 in a Large Cohort of Previously Infected Persons
A total of 6.3% of 2,547 healthcare workers and first responders in the New York City and Detroit metropolitan areas with previous confirmed SARS-CoV-2 infection were seronegative. Among symptomatic persons, the proportion seronegative was largely stable between 2 weeks and 90 days following symptom onset. The proportion seronegative ranged from 0% among 79 persons previously…
Revealing Fine-Scale Spatiotemporal Differences in SARS-CoV-2 Introduction and Spread
Analysis of 247 SARS-CoV-2 sequences from two nearby communities in Wisconsin illustrate distinct patterns of viral spread. Though Dane County had the 12th known introduction of SARS-CoV-2 in the US, this did not lead to community spread. 60 miles away, Milwaukee County experienced few introductions followed by extensive community spread. Moreno et al. (Nov 3,…
Repeated Cross-Sectional Sero-Monitoring of SARS-CoV-2 in New York City
Repeat cross-sectional serosurveys conducted from February to July of residual clinical samples from two patient groups in a New York Hospital — 1) an urgent care (UC) group, enriched with COVID-19 cases, and 2) a routine care (RC) group, which resembles the general population — identified seropositive samples from mid-February, though the first case of…
COVID-19 Risk Management and Screening in the Penitentiary Facilities of the Salerno Province in Southern Italy
In serological and molecular testing of inmates and personnel in an Italian prison with rapid serological IgG/IgM tests for SARS-CoV-2, 3 of 485 prisoners had positive serology results. New prisoners had been isolated for 14 days. All prisoners and personnel had negative nasopharyngeal swabs. Pagano et al. (Oct 31, 2020). COVID-19 Risk Management and Screening…
Favorable Outcomes among Neonates Not Separated from Their Symptomatic SARS-CoV-2-Infected Mothers
In France, among 26 SARS-CoV-2 positive mothers and their neonates, nasopharyngeal and anal swabs from neonates at birth, day 3, and weekly if hospital stay was prolonged, only detected one positive PCR test in an anal swab at birth; nasopharyngeal swabs were negative at day 0 and 3. The infant never developed symptoms. None of…
SARS-CoV-2 Transmission during Team-Sport Do Players Develop COVID-19 after Participating in Rugby League Matches with SARS-CoV-2 Positive Players
[Pre-print, not peer-reviewed] Player interaction and proximity analysis of 4 professional rugby matches in which 8 players were retrospectively found to have SARS-CoV-2 suggest that risk of in-game transmission may be minimal. While video footage analysis and GPS data show the positive players were within 2 meters of other players for up to 316 seconds…
Household Transmission of SARS-COV-2 Insights from a Population-Based Serological Survey
[Pre-print, not peer-reviewed] A household serological survey conducted in Geneva from April to June (n=2,267 households) estimated a 17.2% risk of being infected with SARS-CoV-2 by a single household member compared to a 5.1% cumulative infection risk (through June 30th) from exposures outside the household. Infection risk from an infected household member increased with age,…
Clinical Characteristics of Recovered COVID-19 Patients with Re-Detectable Positive RNA Test
Among 262 patients with COVID-19, 14.5% were found to be re-detectable positive (RP) after at least 14 days of follow up. Most RP patients were young (under 60), initially had mild to moderate illness, and had earlier RNA-negative conversion from illness onset (less than 3 weeks) than non-RP patients. All RP patients were readmitted for…
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