Alliance for Pandemic Preparedness

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October 2, 2020

Intention to Participate in a COVID-19 Vaccine Clinical Trial and to Get Vaccinated against COVID-19 in France during the Pandemic

Nearly 75% of respondents in an online survey in France said they were likely to get a COVID-19 vaccine, and almost half indicated they might agree to participate in a clinical trial for the vaccine. The anonymous online survey indicated that healthcare workers were more likely to report that they would get vaccinated or participate…


Effectiveness of Tests to Detect the Presence of SARS-CoV-2 Virus, and Antibodies to SARS-CoV-2, to Inform COVID-19 Diagnosis: A Rapid Systematic Review

A rapid systematic review of both SARS-CoV-2 virus and antibody testing found a sensitivity of 87.8% for an initial RT-PCR test, while sensitivity of antibody tests ranged from 18.4% to 96.1% and specificity ranged from 88.9% to 100%. The authors note that estimates of diagnostic accuracy should be interpreted cautiously due to the lack of…


Viral Genomes Reveal Patterns of the SARS-CoV-2 Outbreak in Washington State

[Pre-print, not peer reviewed] The 614G viral variant of SARS-CoV-2 has been hypothesized to be more transmissible than other strains, but findings from Washington State indicate that the increasing dominance of 614G in the state is more likely due to mobility patterns and the effect of control measures rather than viral transmissibility factors. Sequencing of…


October 1, 2020

National Trends of Cases of COVID-19 in Children Based on US State Health Department Data

As of Sept 10, 2020, there were 549,432 cumulative COVID-19 cases in the US among children (729 cases per 100,000 children). The geographic focus of case growth shifted from the Northeast in April to the South and West in June and to the Midwest in July. Over time, the proportion of pediatric COVID-19 cases has…


Opioid Overdose–Related Emergency Department Visits and Accidental Deaths during the COVID-19 Pandemic

Emergency room visits and deaths related to opioid overdose increased in San Francisco during the first weeks of COVID-19 pandemic (January 1 through April 18, 2020). Visits related to opioid overdose were 2.5 patients per day during this period vs. 1.4 prior, and deaths were 1.47 per day during this period vs. 0.95 prior. Rodda et…


Exploring U.S. Shifts in Anti-Asian Sentiment with the Emergence of COVID-19.

A racial sentiment analysis using >3.3 million race-related tweets from Twitter users in the US showed the proportion of negative tweets referencing Asians since the emergence of COVID-19 has increased by 68% (from 10% in November 2019 to 16% in March 2020). Common themes that emerged during the content analysis of a random subsample of…


Widening the Gap Greater Racial and Ethnic Disparities in COVID-19 Burden after Accounting for Missing Race/ethnicity Data

[Preprint, not peer-reviewed] Among 19,637 cases of SARS-CoV-2 infection reported in Fulton County, Georgia from February 29th to August 19th 2020, 36% were missing race/ethnicity information in the case report. Compared to complete case analyses, imputation and bias-adjustment for race/ethnicity yielded higher estimates of infection rates (1.5 to 1.8-fold increase). The magnitude of the absolute…


CDC Deployments to State, Tribal, Local, and Territorial Health Departments for COVID-19 Emergency Public Health Response — United States, January 21–July 25, 2020

The US CDC deployed 208 teams to assist 55 state, tribal, local, and territorial health departments with COVID-19 emergency public health response activities between January 21–July 25, 2020. Teams assisted with investigations of transmission in high-risk congregate settings, including long-term care facilities (53 deployments; 26%), food processing facilities (24; 12%), correctional facilities (12; 6%), and…


Reductions in 2020 US Life Expectancy Due to COVID-19 and the Disproportionate Impact on the Black and Latino Populations

[Preprint, not peer-reviewed] Black and Latino people in the US are estimated to have a reduction in life expectancy at birth due to COVID-19 of 2.7 and 3.7 years, respectively, both of which are larger than the 0.84-year reduction for white people. These projections imply a 50% increase (from 3.6 to 5.5 years) in the…


Mental Health of Undocumented College Students during the COVID-19 Pandemic

[Preprint, not peer-reviewed] An online survey in Delaware found significantly higher levels of anxiety and depression among undocumented college students (n=109) compared to the expected proportion based on a large national survey of mental health among college students in US during the COVID-19 pandemic (47% vs. 31% for anxiety; 63% vs 41% for depression, respectively)….



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