Alliance for Pandemic Preparedness

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August 25, 2020

Staying Home, Staying Safe? A Short-Term Analysis of COVID-19 on Dallas Domestic Violence

Piquero et al. compared data from Dallas, Texas on domestic violence crimes for an 83-day period prior to the stay-at-home mandate to a 35-day period thereafter and found evidence suggesting a short-term increase in domestic violence incident reports during the first two weeks following the mandate. Piquero et al. (Aug 14, 2020). Staying Home, Staying…


Follow-up Study of the Pulmonary Function and Related Physiological Characteristics of COVID-19 Survivors Three Months after Recovery

Zhao et al. evaluated COVID-19 survivors (n=55) three months after hospital discharge, none of whom had required mechanical ventilation, and found pulmonary function abnormalities in 14 (25%) despite a lower prevalence of respiratory symptoms (shortness of breath with exertion 15%, cough, and sputum 2%). Thirty-nine participants (71%) had pulmonary abnormalities visible on high-resolution computed tomography….


Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses

Preliminary findings from a cohort study of 192 children (mean age 10.2 +/- 7 years) hospitalized with COVID-19 in Massachusetts show that among participants with acute SARS-CoV-2 infection (n=49) viral load in respiratory secretions in the first 2 days of symptoms was significantly higher compared to that of hospitalized adults with severe disease and more…


More than Loss of Taste and Smell: Burning Watering Eyes in Coronavirus Disease 19

A prospective, observational study of 108 non-hospitalized patients with COVID-19 found 69% reported at least one ocular symptom, the most common being burning sensations (n=39), excessive tearing (n=37), and redness (n=28). Rokohl et al. (Aug 20, 2020). More than Loss of Taste and Smell: Burning Watering Eyes in Coronavirus Disease 19 (COVID-19). Clinical Microbiology and…


Universal Testing for Coronavirus Disease 2019 in Pregnant Women Admitted for Delivery: Prevalence of Peripartum Infection and Rate of Asymptomatic Carriers at Four New York Hospitals within an Integrated Healthcare System

Blitz et al. conducted a retrospective cohort study evaluating women admitted for delivery at 4 hospitals in a New York health system between April 2-9 (n=382) and found a 19% prevalence of COVID-19. Hispanic and non-Hispanic black women were found to be disproportionately affected, and asymptomatic carriers were common (70%) across all 4 sites. Blitz…


Diagnostic Yield of Repeat Testing for SARS-CoV-2: Experience from a Large Health System in Los Angeles

Adamson et al. conducted a retrospective analysis of 10,165 SARS-CoV-2 test results from the UCLA Health System to determine the diagnostic yield of repeat testing and found that among 808 patients who did repeat testing following an initial negative test, only 2% subsequently tested positive. Investigators suggest certain clinical scenarios may benefit from repeat testing,…


Prevalence of SARS-CoV-2 Infection in Children Without Symptoms of Coronavirus Disease 2019

• The prevalence of SARS-CoV-2 infection in asymptomatic children (n=33,041) from across the US who were tested for SAR-CoV-2 when presenting for surgical or medical care was strongly correlated with the prevalence of SARS-CoV-2 in the general population in the communities in which the children lived. The authors present a method to estimate the prevalence…


Phylogenetic Analysis of SARS-CoV-2 in the Boston Area Highlights the Role of Recurrent Importation and Superspreading Events

[pre-print, not peer-reviewed] Lemieux et al. conducted phylogenetic analyses on 772 complete SARS-CoV-2 genomes from the Boston area and found that, since the beginning of the epidemic, there were over 80 introductions into the Boston area, primarily from other parts of the United States and Europe. Investigators studied two distinct superspreading events captured in the…


Time Course of a Second Outbreak of COVID-19 in Beijing, China

After 56 consecutive days of no local transmission events of COVID-19 in Beijing, a new case was diagnosed on June 11, triggering an outbreak alert. The first 2 confirmed cases were found to have epidemiologic links to a local market, which was shut down on June 12. Among the 368 people who tested positive and…


Mask Wearing and Control of SARS-CoV-2 Transmission in the United States

[pre-print, not peer-reviewed] Using weekly longitudinal survey results on face mask wearing, US states with higher levels of face mask wearing were more likely to have a SARS-CoV-2 effective reproductive number (Rt) less than 1, which would lead to control of community transmission. A 10% increase in mask wearing was associated with a higher likelihood…



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