Article Summary
August 17, 2020
Disparities in Incidence of COVID-19 Among Underrepresented Racial/Ethnic Groups in Counties Identified as Hotspots During June 5–18, 2020 — 22 States, February–June 2020
Moore et al. calculated the disparities in COVID-19 cases among underrepresented racial/ethnic groups in 76 counties in 22 US states identified as hotspots during June 5–18, 2020. They report that 76 (96%) analyzed hotspot counties had disparities in cases identified among underrepresented racial/ethnic groups during February–June 2020: 59 (75%) counties had disparities among Hispanic residents; 22 (28%) among black residents;…
Racial and Ethnic Disparities Among COVID-19 Cases in Workplace Outbreaks by Industry Sector — Utah, March 6–June 5, 2020
During March 6–June 5, 2020, Utah reported 1,389 COVID-19 cases associated with 210 workplace-related outbreaks, defined as the occurrence of two or more laboratory-confirmed cases occurring within the same 14-day period among coworkers in a common workplace (median cases per outbreak=4; range=2–79) involving 15 industry sectors, most frequently in manufacturing (20%), construction (15%), and wholesale trade (14%). In total,…
August 14, 2020
Risk of Fomite-Mediated Transmission of SARS-CoV-2 in Child Daycares Schools and Offices a Modeling Study
[preprint, not peer-reviewed] Kraay et al. used a transmission modeling approach to simulate fomite transmission of SARS-CoV-2 (via contaminated surfaces) under a variety of settings, surface types and cleaning frequencies. Unknown parameter values were derived from other pathogens with similar properties to SARS-CoV-2. Fomite R0 ranged from 2 in low risk venues (offices) to 20 in high-risk settings (daycares) and was higher…
Exacerbation of Physical Intimate Partner Violence during COVID-19 Lockdown
An analysis of patients at a Boston hospital found a 1.8-fold higher incidence of intimate partner violence during the early COVID-19 pandemic (March 11 to May 3, 2020) (n=26), compared to the same period over the past three years (n=42). The severity of abuse also increased. Abuse victims were more likely to be ethnically white (65% during 2020 versus 26% during the reference period). Gosangi et…
Associations of Type 1 and Type 2 Diabetes with COVID-19-Related Mortality in England: A Whole-Population Study
A study of all adults registered with a general practice in England (n=61,414,470) found a 2.9-fold higher likelihood of in-hospital COVID-19 related death among those with for type 1 diabetes and 1.8-fold higher likelihood among those with type 2 diabetes compared to other patients, after adjustment for confounders. The unadjusted risk difference for COVID-19 related mortality was…
Racial and Ethnic Disparities in SARS-CoV-2 Pandemic: Analysis of a COVID-19 Observational Registry for a Diverse US Metropolitan Population
A cross-sectional analysis of the COVID-19 Surveillance and Outcomes Registry, which captures data for a large healthcare system in the Houston area, reported a 7% test positivity. After adjustment for confounders, compared to non-Hispanic whites, test positivity was higher among non-Hispanic Black individuals (OR=2.2) and those of Hispanic ethnicity (OR=1.95). Using structural equation modeling, the authors demonstrated a significant indirect effect of…
Characteristics and Outcomes of COVID-19 Patients During Initial Peak and Resurgence in the Houston Metropolitan Area
A review of patients with confirmed COVID-19 in Houston, Texas during the initial peak and resurgence of COVID-19 (up to July 7) found that during the resurgence, patients were younger, more likely to be Hispanic, more likely to reside in a zip code with lower median income, and less likely to have general and specific…
Association Between Number of In-Person Health Care Visits and SARS-CoV-2 Infection in Obstetrical Patients
A nested case-control study among obstetrical patients delivering at four hospitals in Boston found that there was no meaningful difference between the number of in-person visits for case patients with SARS-CoV-2 versus controls (mean 3.3 visits versus 3.1). All patients in the study were tested for SARS-CoV-2 on admission. Cases were matched with up to 5 controls…
Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes
Xia et al. report interim analyses of an ongoing randomized, double-blind, placebo-controlled phase 1 (n=96) and 2 (n=224) clinical trials of an inactivated whole-virus COVID-19 vaccine conducted in Henan Province, China. All participants who were randomized completed the trial up to 28 days post-vaccination. Frequency of adverse reactions increased with dose and the most common adverse reactions were injection…
Phase 1/2 Study of COVID-19 RNA Vaccine BNT162b1 in Adults
Mulligan et al. report safety, tolerability, and immunogenicity findings from an ongoing placebo-controlled observer-blinded dose escalation study among 45 healthy adults randomized to receive an anti-SARS-CoV-2 vaccine that targets the spike glycoprotein receptor-binding domain (two doses 21 days apart). Local reactions and systemic events were generally mild, dose-dependent, and transient. Exceptions included one report of severe…
Previous page Next page