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March 9, 2020
Estimating the burden of United States workers exposed to infection or disease: a key factor in containing risk of COVID-19 infection
Baker et al used data from Bureau of Labor Statistics to estimate the burden of US workers exposed to infection and disease in the workplace. They report that up to 10% (14.4 M) and 18% (26.7M) of Americans are employed in occupations where exposure to disease or infection occurs at least once per week and…
Evaluation of the incidence of COVID-19 and of the efficacy of contention measures in Spain: a data-driven approach
Much still remains unknown about the natural history of the disease. There is need to get insights into mobility-mediated transmission dynamics and it potential use in the containment of the epidemic. Aleta and Moreno using data-driven modelling, studied limiting mobility as containment strategies that could be implemented to stop large-scale spreading of the disease. Aleta…
Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, China
Wang et al compared epidemiological characteristics across periods and different demographic groups using data on 25,961 laboratory-confirmed COVID-19 cases. They used SEIR model to study the epidemic and evaluate the impact of non-pharmaceutical interventions. With interventions, the effective reproductive number dropped from 3.86 to 0.32 and was estimated to prevent 94.5% infections until February 18….
The timing of one-shot interventions for epidemic control
The apparent early success in China’s large-scale intervention to control the COVID-19 epidemic has led to interest in whether other countries can replicate it. In their paper, Lauro et al studied the impact of a single short-term intervention on an epidemic and offer insight into how best to time an intervention whose impact on society…
Transmission of corona virus disease 2019 during the incubation period may lead to a quarantine loophole
Xia et al report that transmission of COVID-9 may occur among close contacts during the incubation period, which may lead to a quarantine loophole. They suggest strong and effective countermeasures be implemented to prevent or mitigate asymptomatic transmission during the incubation period in populations at high risk. Li et al. (Mar 8, 2020). Transmission of…
Modeling the Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19
Peak et al examined the effectiveness of NPI on containing an outbreak of COVID-19. They found that with a short serial interval (4.8 days), individual quarantine can be an effective tool for outbreak containment in settings with high intervention implementation (at least 75% of infected contacts identified and quarantined). In areas where intervention performance is…
March 6, 2020
Psychological impact of the coronavirus disease 2019 (COVID-19) outbreak on healthcare workers in China
Several studies in recent weeks have touched on the psychological effects of the current outbreak on healthcare workers (HCWs), especially in China. Two new questionnaire-based studies have evaluated psychological distress in HCWs. Dai et al found that the top concerns among HCWs were infection of colleagues and family members, protective measures, and medical violence. 39.1%…
Gender differences in patients with COVID-19: Focus on severity and mortality
While men and women appear to have the same susceptibility to COVID-19, men appear to be at greater risk of higher severity and death, in line with prior reports and historical data for SARS-CoV. Jin et al. (Mar 5, 2020). Gender differences in patients with COVID-19: Focus on severity and mortality. Pre-print downloaded Mar 6…
Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China
36 fatal COVID-19 cases are described. All cases progressed to acute respiratory distress syndrome (ARDS) with a median time from onset to ARDS of 11 days. Huang et al. (Mar 5, 2020). Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China. Pre-print downloaded Mar 6 from https://doi.org/10.1101/2020.02.27.20029009
Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19—A single center, retrospective study
In a review of 101 fatal COVID-19 cases, respiratory failure was noted in 100/101 cases while acute cardiac and kidney damage or failure were also identified as key factors in cause of death. Shi et al. (Mar 6, 2020). Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19—A single center, retrospective study. Pre-print downloaded Mar…
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