Article Summary
March 6, 2020
Caution: The clinical characteristics of COVID-19 patients at admission are changing
A new study out of China compared symptoms at admission during early and late periods of the current COVID-19 outbreak. The authors report differences in symptom (e.g., systemic symptoms, such as fever, were more common in the early group but more severe in the later), suggesting that viral mutation may be responsible for changing symptom…
Adjusted age-specific case fatality ratio during the COVID-19 epidemic in Hubei, China, January and February 2020
Severe COVID-19 illness has been documented differently across age groups, but case fatality estimates have not previously accounted for differences by age. This report estimates an overall case fatality of 1.6% (1.4-1.8) in Hubei across both symptomatic and asymptomatic cases. Among those with symptoms, the case fatality is estimated at 3.3% (2.9-2.8) with a dramatic…
Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
While the effects of COVID-19 on kidney function and subsequent effects of renal failure on broader multi-organ failure have been previously discussed, this study suggests that acute renal failure may also serve as a good prognostic indicator. Furthermore, the infection of kidney tubules may indicate the potential for transmission via urine, though further study is…
Validity of Wrist and Forehead Temperature in Temperature Screening in the General Population During the Outbreak of 2019 Novel Coronavirus: a prospective real-world study
528 participants were included in a study assessing the accuracy and precisions of forehead and wrist temperatures measurements. Wrist measurements appear to be more stable under different circumstances for people outdoors. Both measurements were accurate for people indoors. Chen et al. (Mar 6, 2020). Validity of Wrist and Forehead Temperature in Temperature Screening in the…
March 5, 2020
2019 novel coronavirus is undergoing active recombination
Recent news reports and some scientific literature has begun to explore patterns of genetic recombination of SARS-CoV-2. Two new reports provide evidence of such recombination, which is relevant to public health and health care professionals in that such viral changes could influence the accuracy of testing assays, change transmission dynamics, and influence treatment efficacy. Yi…
Risk of COVID-19 for patients with cancer
Authors discuss the need for special considerations when working with cancer patients during the current COVID-19 outbreak. Wang and Zhang (Mar 3, 2020). Risk of COVID-19 for patients with cancer. Lancet Oncol. https://doi.org/10.1016/S1470-2045(20)30149-2
Transmission routes of 2019-nCoV and controls in dental practice
Authors provide specific recommendations for limiting transmission of COVID-19 in dental clinics and hospitals. Peng et al. (Mar 3, 2020). Transmission routes of 2019-nCoV and controls in dental practice. International Journal of Oral Science. https://doi.org/10.1038/s41368-020-0075-9
Guidelines for pregnant women with suspected SARS-CoV-2 infection
Two articles describe special considerations for pregnant women diagnosed with COVID-19. They offer recommendations for maternal and infant safety before, during, and after delivery. Favre et al. (Mar 3, 2020). Guidelines for pregnant women with suspected SARS-CoV-2 infection. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30157-2 Chua et al. (Mar 4, 2020). From the frontlines of COVID-19 – How…
Liver injury in COVID-19: management and challenges
This brief review of the current literature examines the prevalence of pre-existing liver conditions among COVID-19 patients and the incidence of abnormal liver function identified during the course of illness. Potential causes of abnormal liver function are discussed. Zhang et al. (Mar 4, 2020). Liver injury in COVID-19: management and challenges. Lancet Gatroenterol Hepatol. https://doi.org/10.1016/S2468-1253(20)30057-1
CT Imaging and Differential Diagnosis of COVID-19
COVID-19 CT imaging is compared to imaging of other respiratory diseases, with authors providing some case reviews and recommendations for differential diagnostic processes. Dai et al. (Mar 4, 2020). CT Imaging and Differential Diagnosis of COVID-19. Canadian Association of Radiologists Journal. https://doi.org/10.1177%2F0846537120913033
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